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Georgiy
Belogurov
Ph.D. M.S.- Moscow State University, School of Chemistry, Russia, 1997 Ph.D. - University of Turku, Dept. of Biochemistry and Food Chemistry, Finland, 2005 Postdoc - Ohio State Univesity, Dept. of Microbiology, USA, 2006-2009 Principal investigator - University of Turku, Dept. of Biochemistry and Food Chemistry, Finland, 2009- Research interests Bacterial transcription, enzyme kinetics, protein chemistry, phylogenomics, membrane proteins |
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Address University of Turku, Dept. of Biochemistry and Food Chemistry, Vatselankatu 2, Turku FIN-20014, Finland. E-mail: gebelo(at)utu.fi tel.: +358-2-333-6855 Affiliations Academy of Finland Research Fellow Turku Collegium for Science and Medicine National Graduate School in Informational and Structural Biology Systems Biology Research Program |
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Research MULTISUBUNIT RNA POLYMERASE: understanding the mechanistic essentials of transcription (RNAP group homepage) |
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Publications
Belogurov G. A., Sevostyanova A., Svetlov V., Artsimovitch I. (2010). Functional regions of the N-terminal domain of the antiterminator RfaH. Mol. Microbiol. 76 (2): 286-301 [PubMed] Belogurov, G.A., Vassylyeva, M.N. Sevostyanova, A., Xiang, A., Lira, R., Webber, S., Klyuyev, S., Artsimovitch, I., Vassylyev, D.G. (2009) Transcription inactivation through local refolding of the RNA polymerase structure. Nature 457(7227): 332-335 [PubMed] Jämsen J., Tuominen H., Salminen A., Belogurov G.A., Magretova N.N., Baykov A.A., Lahti R. (2007) A CBS domain-containing pyrophosphatase of Moorella thermoacetica is regulated by adenine nucleotides. Biochem J. 408(3):327-33 [PubMed] Belogurov G. A., Vassylyeva M.N., Svetlov V., Klyuyev S., Grishin N.V., Vassylyev D.G., Artsimovitch I. (2007) Structural basis for converting a general transcription factor into an operon-specific virulence regulator. Mol Cell. 26(1):117-29 [PubMed] Malinen A. M., Belogurov G. A., Baykov A. A., Lahti R. (2007) Na+-pyrophosphatase: a novel primary sodium pump. Biochemistry 46(30):8872-8 [PubMed] Belogurov, G. A., Malinen, A. M., Turkina, M. V., Jalonen, U., Rytkönen, K., Baykov, A. A., Lahti, R. (2005) Membrane-bound pyrophosphatase of Thermotoga maritima requires sodium for activity. Biochemistry 44(6): 2088-2096 [PubMed] Malinen, A. M., Belogurov, G. A., Salminen, M., Baykov, A. A. and Lahti, R. (2004) Elucidating the role of conserved glutamates in H+-pyrophosphatase of Rhodospirillum rubrum. J. Biol. Chem. 279: 26811-26816 [PubMed] Belogurov, G. A. and Lahti, R. (2002) A Lysine substitute for K+: A460K mutation eliminates K+-dependence in H+-pyrophosphatase of Carboxydothermus hydrogenoformans. J. Biol. Chem. 277: 49651-49654 [PubMed] Belogurov, G. A., Turkina, M. V., Penttinen, A., Huopalahti, S., Baykov, A. A. and Lahti, R. (2002) H+-Pyrophosphatase of Rhodospirillum rubrum: High-yield expression in Escherichia coli and identification of the Cys residues responsible for inactivation by mersalyl. J. Biol. Chem. 277: 22209-22214 [PubMed] Belogurov G. A., Fabrichniy I. P., Pohjanjoki P., Kasho V. N., Lehtihuhta E., Turkina M. V., Cooperman B. S., Goldman A., Baykov A.A., Lahti R. (2000) Catalytically important ionizations along the reaction pathway of yeast pyrophosphatase. Biochemistry 39(45):13931-13938 [PubMed] |